EBM Publications
We gratefully acknowledge the financial support by the German Research Foundation (DFG) project 460333672 CRC1540 EBM.
2025 Böhringer D. , Cóndor M. , Bischof L. , Czerwinski T. , Gampl N. , Ngo P. , Bauer A. , Bosch-Voskens C. , Lopez Posadas R. , Franze K. , Budday S. , Mark C. , Fabry B. , Gerum R. :Dynamic traction force measurements of migrating immune cells in 3D matrices 2025 )10.1101/2022.11.16.516758 Czerwinski T. , Bischof L. , Böhringer D. , Kara-Kocak S. , Strissel P. , Strick R. , Winterl A. , Gerum R. , Wittmann E. , Schneider M. , Beckmann M. , Nusser G. , Wiesinger M. , Budday S. , Lux A. , Bosch-Voskens C. , Fabry B. , Mark C. :Immune cells employ intermittent integrin-mediated traction forces for 3D migration 2025 )10.1101/2023.04.20.537658 Kreysing EM. , Gautier H. , Humphrey R. , Mooslehner K. , Muresan L. , Haarhoff D. , Mukherjee S. , Zhao X. , Winkel AK. , Dimitracopoulos A. , Pillai EK. , Karadottir RT. , Franze K. :Environmental stiffness regulates neuronal maturation via Piezo1-mediated TTR activity 2025 )10.1101/2024.07.25.605128 Pillai EK. , Mukherjee S. , Gampl N. , McGinn R. , Mooslehner K. , Becker J. , Thompson AJ. , Franze K. :Long-range chemical signallingin vivois regulated by mechanical signals 2025 )10.1101/2024.02.15.580459 Sipkova J. , Franze K. :Eph/ephrin signalling in the developing brain is regulated by tissue stiffness 2025 )10.1101/2024.02.15.580461 Wilm F. , Ammeling J. , Öttl M. , Fick RHJ. , Aubreville M. , Breininger K. :Rethinking U-net Skip Connections for Biomedical Image Segmentation 2025 )10.48550/arXiv.2402.08276 Wilm F. , Öttl M. , Aubreville M. , Breininger K. :Domain and Content Adaptive Convolutions for Cross-Domain Adenocarcinoma Segmentation 2025 )10.48550/arXiv.2409.09797 Öttl M. , Mei S. , Wilm F. , Steenpaß J. , Rübner M. , Hartmann A. , Beckmann M. , Fasching P. , Maier A. , Erber R. , Breininger K. :Analysing Diffusion Segmentation for Medical Images 2025 )10.48550/arXiv.2403.14440 Öttl M. , Wilm F. , Steenpaß J. , Qiu J. , Rübner M. , Hartmann A. , Beckmann M. , Fasching P. , Maier A. , Erber R. , Kainz B. , Breininger K. :Style-Extracting Diffusion Models for Semi-supervised Histopathology Segmentation 18th European Conference on Computer Vision, ECCV 2024 (Milan 29. September 2024 - 4. Oktober 2024 )In: Aleš Leonardis, Elisa Ricci, Stefan Roth, Olga Russakovsky, Torsten Sattler, Gül Varol (Hrsg.): Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 2025 10.1007/978-3-031-73226-3_14 2024 Almahayni K. , Bachir Salvador J. , Conti R. , Widera A. , Spiekermann M. , Wehner D. , Grützmacher H. , Möckl L. :Tailored Bisacylphosphane Oxides for Precise Induction of Oxidative Stress-Mediated Cell Death in Biological Systems ACS Chemical Biology 2024 )ISSN: 1554-8929 10.1021/acschembio.4c00399 Aubreville M. , Stathonikos N. , Donovan TA. , Klopfleisch R. , Ammeling J. , Ganz J. , Wilm F. , Veta M. , Jabari S. , Eckstein M. , Annuscheit J. , Krumnow C. , Bozaba E. , Çayır S. , Gu H. , Chen X‘. , Jahanifar M. , Shephard A. , Kondo S. , Kasai S. , Kotte S. , Saipradeep VG. , Lafarge MW. , Koelzer VH. , Wang Z. , Zhang Y. , Yang S. , Wang X. , Breininger K. , Bertram CA. :Domain generalization across tumor types, laboratories, and species — Insights from the 2022 edition of the Mitosis Domain Generalization Challenge Medical Image Analysis 94 2024 ), Art.Nr.: 103155 ISSN: 1361-8415 10.1016/j.media.2024.103155 Bergs J. , Morr AS. , Silva RV. , Infante-Duarte C. , Sack I. :The Networking Brain: How Extracellular Matrix, Cellular Networks, and Vasculature Shape the In Vivo Mechanical Properties of the Brain Advanced Science 11 2024 ), Art.Nr.: 2402338 ISSN: 2198-3844 10.1002/advs.202402338 Boßelmann CM. , Leu C. , Brünger T. , Hoffmann L. , Baldassari S. , Chipaux M. , Coras R. , Kobow K. , Hamer H. , Delev D. , Rössler K. , Bien CG. , Kalbhenn T. , Pieper T. , Hartlieb T. , Becker K. , Ferguson L. , Busch RM. , Baulac S. , Nuernberg P. , Najm I. , Blümcke I. , Lal D. :Analysis of 1386 epileptogenic brain lesions reveals association with DYRK1A and EGFR Nature Communications 15 2024 ), Art.Nr.: 10429 ISSN: 2041-1723 10.1038/s41467-024-54911-w Braun J. , Bernarding J. , Snellings J. , Meyer T. , Dantas de Moraes PA. , Safraou Y. , Wells RG. , Guo J. , Tzschaetzsch H. , Zappe A. , Pagel K. , Sauer IM. , Hillebrandt KH. , Sack I. :On the relationship between viscoelasticity and water diffusion in soft biological tissues Acta Biomaterialia 182 2024 ), S. 42-53 ISSN: 1742-7061 10.1016/j.actbio.2024.05.007 Chakraborti S. , Zaburdaev V. :Transport in cellular aggregates described by fluctuating hydrodynamics Physical Review Research 6 2024 ), Art.Nr.: 043064 ISSN: 2643-1564 10.1103/PhysRevResearch.6.043064 Fabian M. , Rajput JR. , Schüre JR. , Weinmüller S. , Mennecke A. , Möhle TA. , Rampp S. , Schmidt M. , Dörfler A. , Zaiß M. :Comprehensive 7 T CEST: A clinical MRI protocol covering multiple exchange rate regimes NMR in Biomedicine 2024 )ISSN: 0952-3480 10.1002/nbm.5096 Firooz S. , Reddy BD. , Zaburdaev V. , Steinmann P. :Mean zero artificial diffusion for stable finite element approximation of convection in cellular aggregate formation Computer Methods in Applied Mechanics and Engineering 419 2024 ), S. 116649 ISSN: 0045-7825 10.1016/j.cma.2023.116649 Franze K. :Tensed axons are on fire Proceedings of the National Academy of Sciences of the United States of America 121 2024 ), S. e2321811121 ISSN: 0027-8424 10.1073/pnas.2321811121 Greiner A. , Reiter N. , Hinrichsen J. , Kainz MP. , Sommer G. , Holzapfel GA. , Steinmann P. , Comellas E. , Budday S. :Model-driven exploration of poro-viscoelasticity in human brain tissue: be careful with the parameters! Interface Focus 14 2024 )ISSN: 2042-8901 10.1098/rsfs.2024.0026 Gutmann M. , Salvador JB. , Müller P. , Kim K. , Schicht M. , Aif S. , Paulsen F. , Meinel L. , Guck J. , Möllmert S. :Beyond comparison: Brillouin microscopy and AFM-based indentation reveal divergent insights into the mechanical profile of the murine retina JPhys Photonics 6 2024 ), Art.Nr.: 035020 ISSN: 2515-7647 10.1088/2515-7647/ad5ae3 Hinrichsen J. , Feiler L. , Reiter N. , Bräuer L. , Schicht M. , Paulsen F. , Budday S. :Identifying composition-mechanics relations in human brain tissue based on neural-network-enhanced inverse parameter identification Mathematics and Mechanics of Solids 2024 )ISSN: 1081-2865 10.1177/10812865231206544 Hinrichsen J. , Ferlay C. , Reiter N. , Budday S. :Using dropout based active learning and surrogate models in the inverse viscoelastic parameter identification of human brain tissue Frontiers in Physiology 15 2024 ), Art.Nr.: 1321298 ISSN: 1664-042X 10.3389/fphys.2024.1321298 Jun S. , Jun S. , Herbst A. , Herbst A. , Scheffter K. , John N. , Kolb J. , Wehner D. , Fattahi H. :Nonlinear dynamics of femtosecond laser interaction with the central nervous system in zebrafish Communications Physics 7 2024 ), Art.Nr.: 161 ISSN: 2399-3650 10.1038/s42005-024-01653-2 Kasper BS. , Archer J. , Bernhardt BC. , Caciagli L. , Cendes F. , Chinvarun Y. , Concha L. , Federico P. , Gaillard W. , Kobayashi E. , Ogbole G. , Vaudano A. , Wang I. , Wang S. , Winston G. , Rampp S. :ILAE neuroimaging task force highlight: Subcortical laminar heterotopia Epileptic Disorders 2024 )ISSN: 1294-9361 10.1002/epd2.20206 Kreidenhuber R. , Poppert KN. , Mauritz M. , Hamer H. , Delev D. , Schnell O. , Rampp S. :MEG in MRI-Negative Patients with Focal Epilepsy Journal of Clinical Medicine 13 2024 ), Art.Nr.: 5746 ISSN: 2077-0383 10.3390/jcm13195746 Kuth S. , Boccaccini AR. :Enzymatic Insitu Crosslinking Can Improve Hydrogel Stability While Maintaining Matrix Stiffness ChemistrySelect 9 2024 ), Art.Nr.: e202401700 ISSN: 2365-6549 10.1002/slct.202401700 Lehner A. , Hoffmann L. , Rampp S. , Coras R. , Paulsen F. , Frischknecht R. , Hamer H. , Walther K. , Brandner S. , Hofer W. , Pieper T. , Reisch LM. , Bien CG. , Blümcke I. :Age-dependent increase of perineuronal nets in the human hippocampus and precocious aging in epilepsy Epilepsia Open 9 2024 ), S. 1372-1381 ISSN: 2470-9239 10.1002/epi4.12963 Meyer T. , Castelein J. , Schattenfroh J. , Morr AS. , Da Silva RV. , Tzschaetzsch H. , Reiter R. , Guo J. , Sack I. :Magnetic resonance elastography in a nutshell: Tomographic imaging of soft tissue viscoelasticity for detecting and staging disease with a focus on inflammation Progress in Nuclear Magnetic Resonance Spectroscopy 144-145 2024 ), S. 1-14 ISSN: 0079-6565 10.1016/j.pnmrs.2024.05.002 Möckel C. , Beck T. , Kaliman S. , Abuhattum S. , Kim K. , Kolb J. , Wehner D. , Zaburdaev V. , Guck J. :Estimation of the mass density of biological matter from refractive index measurements Biophysical Reports 2024 ), S. 100156 ISSN: 2667-0747 10.1016/j.bpr.2024.100156 Silva RV. , Morr AS. , Herthum H. , Koch SP. , Mueller S. , Batzdorf CS. , Bertalan G. , Meyer T. , Tzschaetzsch H. , Kuehl AA. , Boehm-Sturm P. , Braun J. , Scheel M. , Paul F. , Infante-Duarte C. , Sack I. :Cortical matrix remodeling as a hallmark of relapsing–remitting neuroinflammation in MR elastography and quantitative MRI Acta Neuropathologica 147 2024 ), Art.Nr.: 8 ISSN: 0001-6322 10.1007/s00401-023-02658-x Vorndran J. , Blümcke I. :A deep‐learning‐based histopathology classifier for focal cortical dysplasia (FCD) unravels a complex scenario of comorbid FCD subtypes Epilepsia 2024 )ISSN: 0013-9580 10.1111/epi.18161 Wilm F. , Reimann MK. , Taubmann O. , Mühlberg A. , Breininger K. :Appearance-based Debiasing of Deep Learning Models in Medical Imaging German Conference on Medical Image Computing, BVM 2024 (Erlangen 10. März 2024 - 12. März 2024 )In: Andreas Maier, Thomas M. Deserno, Heinz Handels, Klaus Maier-Hein, Christoph Palm, Thomas Tolxdorff (Hrsg.): Bildverarbeitung für die Medizin 2024. BVM 2024 , Wiesbaden 2024 10.1007/978-3-658-44037-4_9 2023 Aubreville M. , Wilm F. , Stathonikos N. , Breininger K. , Donovan TA. , Jabari S. , Veta M. , Ganz J. , Ammeling J. , van Diest PJ. , Klopfleisch R. , Bertram CA. :A comprehensive multi-domain dataset for mitotic figure detection Scientific Data 10 2023 ), Art.Nr.: 484 ISSN: 2052-4463 10.1038/s41597-023-02327-4 Bertalan G. , Becker J. , Tzschätzsch H. , Morr A. , Herthum H. , Shahryari M. , Greenhalgh RD. , Guo J. , Schröder L. , Alzheimer C. , Budday S. , Franze K. , Braun J. , Sack I. :Mechanical behavior of the hippocampus and corpus callosum: An attempt to reconcile ex vivo with in vivo and micro with macro properties Journal of the Mechanical Behavior of Biomedical Materials 138 2023 ), Art.Nr.: 105613 ISSN: 1751-6161 10.1016/j.jmbbm.2022.105613 Firooz S. , Javili A. , Steinmann P. :A versatile implicit computational framework for continuum-kinematics-inspired peridynamics Computational Mechanics 2023 )ISSN: 0178-7675 10.1007/s00466-023-02415-7 Flaschel M. , Yu H. , Reiter N. , Hinrichsen J. , Budday S. , Steinmann P. , Kumar S. , De Lorenzis L. :Automated discovery of interpretable hyperelastic material models for human brain tissue with EUCLID Journal of the Mechanics and Physics of Solids 180 2023 ), Art.Nr.: 105404 ISSN: 0022-5096 10.1016/j.jmps.2023.105404 Hinrichsen J. , Reiter N. , Bräuer L. , Paulsen F. , Käßmair S. , Budday S. :Inverse identification of region-specific hyperelastic material parameters for human brain tissue Biomechanics and Modeling in Mechanobiology 2023 )ISSN: 1617-7959 10.1007/s10237-023-01739-w Hoffmann L. , Coras R. , Kobow K. , López-Rivera JA. , Lal D. , Leu C. , Najm I. , Nürnberg P. , Herms J. , Harter PN. , Bien CG. , Kalbhenn T. , Müller M. , Pieper T. , Hartlieb T. , Kudernatsch M. , Hamer H. , Brandner S. , Rössler K. , Blümcke I. , Jabari S. :Ganglioglioma with adverse clinical outcome and atypical histopathological features were defined by alterations in PTPN11/KRAS/NF1 and other RAS-/MAP-Kinase pathway genes Acta Neuropathologica 2023 )ISSN: 0001-6322 10.1007/s00401-023-02561-5 Honke J. , Hoffmann L. , Coras R. , Kobow K. , Leu C. , Pieper T. , Hartlieb T. , Bien CG. , Woermann F. , Cloppenborg T. , Kalbhenn T. , Gaballa A. , Hamer H. , Brandner S. , Rössler K. , Dörfler A. , Rampp S. , Lemke JR. , Baldassari S. , Baulac S. , Lal D. , Nürnberg P. , Blümcke I. :Deep histopathology genotype–phenotype analysis of focal cortical dysplasia type II differentiates between the GATOR1-altered autophagocytic subtype IIa and MTOR-altered migration deficient subtype IIb Acta Neuropathologica Communications 11 2023 ), Art.Nr.: 179 ISSN: 2051-5960 10.1186/s40478-023-01675-x Kolb J. , Tsata V. , John N. , Kim K. , Möckel C. , Rosso G. , Kurbel V. , Parmar A. , Sharma G. , Karandasheva K. , Abuhattum S. , Lyraki O. , Beck T. , Mueller P. , Schlüßler R. , Frischknecht R. , Wehner A. , Krombholz N. , Steigenberger B. , Beis D. , Takeoka A. , Blümcke I. , Möllmert S. , Singh K. , Guck J. , Kobow K. , Wehner D. :Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment Nature Communications 14 2023 ), Art.Nr.: 6814 ISSN: 2041-1723 10.1038/s41467-023-42339-7 Kreitz S. , Mennecke A. , Konerth L. , Rösch J. , Nagel AM. , Laun FB. , Uder M. , Dörfler A. , Heß A. :3T vs. 7T fMRI: capturing early human memory consolidation after motor task utilizing the observed higher functional specificity of 7T Frontiers in Neuroscience 17 2023 )ISSN: 1662-4548 10.3389/fnins.2023.1215400 Kuth S. , Lorke M. , Frischknecht R. , Boccaccini AR. :Tinten für die Biofabrikation–Druckbarkeit vs. Biokompatibilität? BioSpektrum 29 2023 ), S. 736-739 ISSN: 0947-0867 10.1007/s12268-023-2046-0 Pillai EK. , Franze K. :Mechanics in the nervous system: From development to disease Neuron 2023 )ISSN: 0896-6273 10.1016/j.neuron.2023.10.005 Pranavi D. , Steinmann P. , Rajagopal A. :A unifying finite strain modeling framework for anisotropic mixed-mode fracture in soft materials Computational Mechanics 2023 )ISSN: 0178-7675 10.1007/s00466-023-02359-y Reiter N. , Paulsen F. , Budday S. :Mechanisms of mechanical load transfer through brain tissue Scientific Reports 13 2023 ), Art.Nr.: 8703 ISSN: 2045-2322 10.1038/s41598-023-35768-3 Reiter N. , Schäfer AM. , Auer S. , Paulsen F. , Budday S. :Modeling the finite viscoelasticity of human brain tissue based on microstructural information Proceedings in Applied Mathematics and Mechanics 2023 )ISSN: 1617-7061 10.1002/pamm.202300234 Stüfchen I. , Beyer F. , Stäbler S. , Fischer S. , Kappelmann M. , Beckervordersandforth R. , Boßerhoff AK. :Sox9 regulates melanocytic fate decision of adult hair follicle stem cells iScience 26 2023 ), Art.Nr.: 106919 ISSN: 2589-0042 10.1016/j.isci.2023.106919 Sáez P. , Borau C. , Antonovaite N. , Franze K. :Brain tissue mechanics is governed by microscale relations of the tissue constituents Biomaterials 301 2023 ), Art.Nr.: 122273 ISSN: 0142-9612 10.1016/j.biomaterials.2023.122273 Wang DD. , Katoch M. , Jabari S. , Blümcke I. , Blumenthal DB. , Lu DH. , Coras R. , Wang YJ. , Shi J. , Zhou WJ. , Kobow K. , Piao YS. :The specific DNA methylation landscape in focal cortical dysplasia ILAE type 3D Acta Neuropathologica Communications 11 2023 ), Art.Nr.: 129 ISSN: 2051-5960 10.1186/s40478-023-01618-6 Zarzor MS. , Blümcke I. , Budday S. :Exploring the role of the outer subventricular zone during cortical folding through a physics-based model eLife 12 2023 )ISSN: 2050-084X 10.7554/eLife.82925 Zarzor MS. , Steinmann P. , Budday S. :Multifield computational model for human brain development: Explicit numerical stabilization Proceedings in Applied Mathematics and Mechanics 2023 )ISSN: 1617-7061 10.1002/pamm.202300288
