Lab Shadowing: Mechanical Insights into Aging Organoids

Beginning of March, Michael Tranchina (A04) and Nina Reiter (B01, BRAINIACS) performed collaborative experiments to characterize 88-day-old organoids mechanically using a rheometer. In older organoids, the growing necrotic core and the increasing cellular diversity, especially the potential presence of glial cells, can have an influence on the organoids‘ stability and stiffness. The results from our experiments will provide new insights into the mechanical behavior of older organoids.
Michael Tranchina, A04 & Nina Reiter, B01